Image Theses and Dissertations Quantitative scanning microwave microscopy of a biological cell The electromagnetic properties of a live biological system are extremely important to many medical applications. While information about electromagnetic properties of tissues are available in the literature, little or no data are available for a single cell or subcellular structures. Microwave biological/cell detection has been demonstrated to be useful and promising in many medical applications due to its internal properties such as non-invasive, fast and label-free. View Item
Image Theses and Dissertations Dielectric Spectroscopy of Biological Samples For the first time, the impedance spectrum of live Jurkat T-lymphocytes human cells was characterized in a single sweep spanning six decades of frequency from 9 kHz to 9 GHz. The ultrawide bandwidth bridged the traditional impedance spectroscopy at kilohertz to megahertz frequencies with the recently developed microwave dielectric spectroscopy, which can probe the cell interior without being hindered by the cell membrane. View Item
Image Theses and Dissertations Applications of Scanning Microwave Microscopy on Nanoscale Imaging of Biological Samples and CMOS Interconnects In this work, we systematically studied and introduced both AFM-based and STM-based scanning microwave microscopy. CMOS interconnects, single dried cell and organelles like exosomes have been imaged with scanning microwave microscopy.The scanning microwave microscopy of CMOS interconnect aluminum lines both bare and buried under oxide has been achieved. In both cases, a spatial resolution of 190 +- 70 nm was achieved, which was comparable or better than what had been reported in the literature. View Item
Image Theses and Dissertations Design, Fabrication, Characterization and Modeling of CMOS-Compatible PtSe2 MOSFETs For the last 50 years, Si metal-oxide-semiconductor field-effect transistors (MOSFETs) have undergone tremendous development under the Moore's law. However, it has become more and more difficult to continue the scaling due to the limitation of Si quantum confinement when the gate length is less than 5 nm. Two-dimensional (2D) atomic-layered materials may replace Si in future-generation ultra-thin-body, low-power, and high-performance MOSFETs. However, for any 2D material to replace Si, it must not only have high mobility and sizable bandgap, but also be manufacturable. View Item
Image Theses and Dissertations Ultra-wideband Single Jurkat Human T-lymphocyte Cell Characterization, Dielectrophoresis, and Electroporation Using One Vector Network Analyzer For the first time, single-cell trapping, characterization, electroporation, and de-trapping were demonstrated by conveniently programming the frequency and power of the same ultra-wideband vector network analyzer (VNA) to perform the different functions across its bandwidth of 9 kHz‒9 GHz. On one hand, trapping of a live biological cell was accomplished by applying to a coplanar waveguide (CPW) through the VNA a continuous wave (CW) signal of 3 dBm and 5 MHz, corresponding to attractive dielectrophoresis. View Item