Date

2017

Document Type

Thesis

Degree

Master of Science

Department

Bioengineering

First Adviser

Zhou, Chao

Abstract

The study demonstrated OCT angiography on a flowing phantom by calculating the intensity (speckle) variance between repeated frames with motion correction on a subpixel level. Other algorithms had also been tested, including phase variance, complex differential variance and Angio-OCT on both flow phantom and finger of human. The result of 3D phantom experiment and finger experiments proved that SV algorithms and Angio-OCT algorithms can be potentially used in our OCT system for finger angiography. Several different settings including scanning range, scan position density in x and y direction, number of repeated scan to use and other parameters have been tried out to improve the quality of angiographic image quality. The result of finger experiment didn’t fulfill the expectation and the maximum intensity projection of angiographic image was not so clear due to the influence of motion and background noise. Some problems still remain unsolved by far. However, the experiences of data processing especially the process of frame registration lays a foundation for future research.

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